Application of the hottest absciex ion mobility di

2022-07-30
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Breakthrough performance of ab SCIEX ion mobility differential mass spectrometry in quantitative and qualitative analysis ™ Technology. This new technology brings unprecedented performance and breakthrough selectivity to ion mobility mass spectrometry for quantitative and qualitative analysis. Ab SCIEX will present the latest selexion technology at the American Society of mass spectrometry (ASMs) conference in Denver, Colorado this week

SelexION ™ The technology is the first ion mobility differential mass spectrometry separation technology with high reproducibility, durability and ease of use. At the same time, it can also provide more one-dimensional selectivity for high-sensitivity quantitative and qualitative analysis. All these can be used in UHPLC retention time and various multiple reaction monitoring (MRM), It is also called selective reaction monitoring (SRM). It is especially suitable for the separation of isomers, chromatographic separation of outflow impurities and elimination of high background noise ™ The selectivity and detection limit can be significantly improved. Therefore, this progress improves the data quality and simplifies the sample preparation process

the current methods for optimizing selectivity are limited by the separation mode of each compound and chromatographic analysis conditions. It is often not possible to provide sufficient selectivity to eliminate or separate isomer interference or high background noise in complex samples. To address this challenge, ab SCIEX developed selexion ™ Technology also provides a number of factors to improve selectivity based on molecular morphology. Before the common fault 7:ab SCIEX technology provides super selectivity, many complex samples cannot be separated

the new DMS technology is especially suitable for scientists and laboratory chemists in the pharmaceutical and cro drug R & D, food safety and environmental testing industries. These experts are often disturbed by isomers, and it is difficult to separate impurities. A fast, reproducible and easy-to-use method is urgently needed to enhance the selectivity of lc/ms/ms separation, while ensuring high enough sensitivity

dms technology uses the industry-leading mass spectrometry series, namely triplequad ™ 5500 system and qtrap ® 5500 system. AB SCI elongation>350%ex triple Quad 5500 system produces the most accurate quantitative results with the fastest scanning speed in the industry, and uses the lowest concentration to determine a large number of target analytes in complex samples. The ab SCIEX qtrap 5500 system is a unique new generation of mass spectrometer, which utilizes the so-called linear accelerator ™ The linear ion trap technology integrates triple four-stage rod capability. This unique composite system in the market accurately integrates the highest sensitivity and selectivity in the industry in both quantitative and qualitative analysis

pharmacadence analytical services founder and director, Dr. Rick king

"The mass spectrometry of ab SCIEX's differential ion mobility separation technology has greatly improved the selectivity of quantitative and qualitative analysis. Ab SCIEX is constantly committed to providing first-class mass spectrometry tools to solve analysis problems, which has a long history in this field. Using DMS on the triple quadrupole and qtrap 5500 mass spectrometer to provide new analytical selectivity. Increasingly stringent emission standards have put forward higher requirements for automobile manufacturers. In order to obtain complete trust, accuracy and reproduction Please pay close attention to the latest technology of ab SCIEX. "

ab SCIEX, general manager and vice president of pharmaceutical and proteomics business department, Dave hicks

"with the technological breakthrough of selexion, we have exceeded the limits of mass spectrometry in various applications and provided higher selectivity, reproducibility and durability. We have given more powerful 'separation ability' to scientists and chemists, so that they can separate and determine molecules in an unprecedented way."

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